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Polly A Hofmann Selected Research

N-benzyladriamycin-14-valerate (AD 198)

10/2010Protection from doxorubicin-induced cardiomyopathy using the modified anthracycline N-benzyladriamycin-14-valerate (AD 198).
11/2007N-Benzyladriamycin-14-valerate (AD 198): a non-cardiotoxic anthracycline that is cardioprotective through PKC-epsilon activation.

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Polly A Hofmann Research Topics

Disease

5Ischemia
06/2008 - 03/2005
3Inflammation (Inflammations)
01/2017 - 06/2008
2Cardiotoxicity
10/2010 - 11/2007
1Myocarditis (Carditis)
01/2017
1Endotoxemia
07/2013
1Cardiomyopathies (Cardiomyopathy)
10/2010
1Hypoxia (Hypoxemia)
11/2007
1Pathologic Processes
02/2007
1Contracture
03/2005
1Hypothyroidism
07/2003

Drug/Important Bio-Agent (IBA)

2Adrenergic Agents (Adrenergic Drugs)IBA
01/2017 - 07/2003
2Adenosine (Adenocard)FDA LinkGeneric
01/2017 - 07/2013
2Purinergic P1 Receptors (Adenosine Receptor)IBA
07/2013 - 10/2007
2N-benzyladriamycin-14-valerate (AD 198)IBA
10/2010 - 11/2007
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2017
1Apelin ReceptorsIBA
01/2017
1LipopolysaccharidesIBA
07/2013
1AnthracyclinesIBA
10/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2010
1Platelet Activating FactorIBA
06/2008
1Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2008
1Phospholipids (Phosphatides)FDA LinkGeneric
06/2008
1Proteins (Proteins, Gene)FDA Link
06/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2007
1DesminIBA
09/2007
1p38 Mitogen-Activated Protein KinasesIBA
09/2007
1Peptides (Polypeptides)IBA
02/2007
1Myosins (Myosin)IBA
03/2005
1Troponin T (Troponin T1)IBA
03/2005
1Trinitrotoluene (TNT)IBA
03/2005
1Adenosine Triphosphate (ATP)IBA
03/2005
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
07/2003

Therapy/Procedure

1Drug Therapy (Chemotherapy)
10/2010